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(11)

EP 3 337 480 A1

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(43) Date of publication: 27.06.2018 Bulletin 2018/26 (21) Application number: 16836711.8 (22) Date of filing: 04.08.2016

(51) International Patent Classification (IPC):  A61K 31/4415(2006.01) A61K 9/00(2006.01) A61P 1/08(2006.01) C07D 213/67(2006.01) A61K 31/4402(2006.01) A61K 9/08(2006.01) C07D 213/30(2006.01) (86) International application number: PCT/IB2016/054722 (87) International publication number: WO 2017/029573 (23.02.2017 Gazette 2017/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 17.08.2015 US 201562205941 P (71) Applicant: Aequus Pharmaceuticals Inc. Vancouver, BC V6C 1S4 (CA)	(72) Inventors: PLAKOGIANNIS, Fotios, M. Whitestone, NY 11357 (US) MCAFEE, Donald Pt. Roberts, WA 98281 (US) LATHER, Tamanna Jersey City, NJ 07304 (US) BOROVINSKAYA, Marina East Brunswick, NJ 08816 (US) (74) Representative: v. Bezold & Partner Patentanwälte - PartG mbB  Akademiestraße 7 80799 München 80799 München (DE)