| (84) |
Designated Contracting States: |
|
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
18.08.2015 US 201562206776 P 30.10.2015 US 201562249085 P
|
| (43) |
Date of publication of application: |
|
27.06.2018 Bulletin 2018/26 |
| (60) |
Divisional application: |
|
20213720.4 / 3827846 |
| (73) |
Proprietor: Rakuten Medical, Inc. |
|
San Diego, CA 92121 (US) |
|
| (72) |
Inventors: |
|
- BIEL, Merrill
Mendota Heights, MN 51158 (US)
- MAKINGS, Lewis, R.
Encinitas, CA 92024 (US)
- HEIM, Roger
Del Mar, CA 92014 (US)
- GARCIA-GUZMAN, Miguel
San Diego, CA 92130 (US)
- CHIN, Eileen, Sun
San Diego, CA 92121 (US)
- YADAV, Deepak
San Diego, CA 92129 (US)
- FONG, Jerry
San Diego, CA 92130 (US)
|
| (74) |
Representative: J A Kemp LLP |
|
80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB) |
| (56) |
References cited: :
WO-A1-2013/009475 US-A1- 2012 010 558 US-B2- 9 358 306
|
WO-A2-2017/031363 US-A1- 2014 120 119
|
|
| |
|
|
- SATO KAZUHIDE ET AL: "Photoimmunotherapy: Comparative effectiveness of two monoclonal
antibodies targeting the epidermal growth factor receptor", MOLECULAR ONCOLOGY, vol.
8, no. 3, 22 January 2014 (2014-01-22), pages 620-632, XP028640450, ISSN: 1574-7891,
DOI: 10.1016/J.MOLONC.2014.01.006
- MITSUNAGA MAKOTO ET AL: "Cancer cell-selective in vivo near infrared photoimmunotherapy
targeting specific membrane molecules.", NATURE MEDICINE DEC 2011, vol. 17, no. 12,
December 2011 (2011-12), pages 1685-1691, XP002763622, ISSN: 1546-170X
- MAKOTO MITSUNAGA ET AL: "Immediate in vivo target-specific cancer cell death after
near infrared photoimmunotherapy", BMC CANCER, BIOMED CENTRAL, LONDON, GB, vol. 12,
no. 1, 8 August 2012 (2012-08-08) , page 345, XP021120474, ISSN: 1471-2407, DOI: 10.1186/1471-2407-12-345
- ALI A. MAAWY ET AL: "Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results
in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic
Mouse Models of Pancreatic Cancer", PLOS ONE, vol. 10, no. 3, 23 March 2015 (2015-03-23)
, page e0121989, XP55314764, DOI: 10.1371/journal.pone.0121989
- K. SANO ET AL: "The Effect of Photoimmunotherapy Followed by Liposomal Daunorubicin
in a Mixed Tumor Model: A Demonstration of the Super-Enhanced Permeability and Retention
Effect after Photoimmunotherapy", MOLECULAR CANCER THERAPEUTICS, vol. 13, no. 2, 1
February 2014 (2014-02-01), pages 426-432, XP55337451, US ISSN: 1535-7163, DOI: 10.1158/1535-7163.MCT-13-0633
- TAKAHITO NAKAJIMA ET AL: "Improving the Efficacy of Photoimmunotherapy (PIT) using
a Cocktail of Antibody Conjugates in a Multiple Antigen Tumor Model", THERANOSTICS,
vol. 3, no. 6, 1 January 2013 (2013-01-01) , pages 357-365, XP55219807, AU ISSN: 1838-7640,
DOI: 10.7150/thno.5908
- TADANOBU NAGAYA ET AL: "Near Infrared Photoimmunotherapy Targeting EGFR Positive Triple
Negative Breast Cancer: Optimizing the Conjugate-Light Regimen", PLOS ONE, vol. 10,
no. 8, 27 August 2015 (2015-08-27), page e0136829, XP55314754, DOI: 10.1371/journal.pone.0136829
- Ntc02422979: "Study of RM-1929 and Photoimmunotherapy in Patients With Recurrent Head
and Neck Cancer", , 17 April 2015 (2015-04-17), XP055624966, Retrieved from the Internet:
URL:https://clinicaltrials.gov/ct2/history /NCT02422979?V_1=View#StudyPageTop [retrieved
on 2019-09-23]
|
|