ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................*JBDM Ver 2.0.15 (20th of December) - 2999001/03337514CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120220406W173deBibliographieenBibliographyfrBibliographieEP16758029.9201608182018021420190927enenen201562206776 P20150818US201562249085 P20151030US2022040620221420180627201826202203022022092021091320220406202214A61K 47/50 20170101AFI20210226BHEP A61K 47/68 20170101ALI20210226BHEP A61K 41/00 20200101ALI20210226BHEP A61K 38/18 20060101ALI20210226BHEP A61P 35/00 20060101ALI20210226BHEP A61K 47/6803 20170801 LI20170802BHEP A61K 47/6849 20170801 LI20170802BHEP A61K 41/0071 20130101 FI20170426BHEP A61P 35/00 20180101 LI20180906BHEP A61K 38/18 20130101 LA20180906BHEP A61K 47/6851 20170801 LI20191118BHEP Y02A 50/30 20180101 LA20200801RHEP deZUSAMMENSETZUNG AUS EINEM KONJUGAT MIT EINEM PHTHALOCYANINFARBSTOFF, DER MIT EINEM ZIELMOLLEKEL FÜR FOTOIMMUNOTHERAPIE VERBUNDEN ISTenCOMPOSITION COMPRISING A CONJUGATE COMPRISING A PHTHALOCYANINE DYE LINKED TO A TARGETING MOLECULE FOR PHOTOIMMUNOTHERAPYfrCOMPOSITION COMPRENANT UN CONJUGUÉ COMPRENANT UN COLORANT PHTHALOCYANINE LIÉ À UNE MOLÉCULE CIBLE POUR LA PHOTOIMMUNOTHÉRAPIEWO-A1-2013/009475WO-A2-2017/031363US-A1- 2012 010 558US-A1- 2014 120 119US-B2- 9 358 306SATO KAZUHIDE ET AL: "Photoimmunotherapy: Comparative effectiveness of two monoclonal antibodies targeting the epidermal growth factor receptor", MOLECULAR ONCOLOGY, vol. 8, no. 3, 22 January 2014 (2014-01-22), pages 620-632, XP028640450, ISSN: 1574-7891, DOI: 10.1016/J.MOLONC.2014.01.006MITSUNAGA MAKOTO ET AL: "Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules.", NATURE MEDICINE DEC 2011, vol. 17, no. 12, December 2011 (2011-12), pages 1685-1691, XP002763622, ISSN: 1546-170XMAKOTO MITSUNAGA ET AL: "Immediate in vivo target-specific cancer cell death after near infrared photoimmunotherapy", BMC CANCER, BIOMED CENTRAL, LONDON, GB, vol. 12, no. 1, 8 August 2012 (2012-08-08) , page 345, XP021120474, ISSN: 1471-2407, DOI: 10.1186/1471-2407-12-345ALI A. MAAWY ET AL: "Near Infra-Red Photoimmunotherapy with Anti-CEA-IR700 Results in Extensive Tumor Lysis and a Significant Decrease in Tumor Burden in Orthotopic Mouse Models of Pancreatic Cancer", PLOS ONE, vol. 10, no. 3, 23 March 2015 (2015-03-23) , page e0121989, XP55314764, DOI: 10.1371/journal.pone.0121989K. SANO ET AL: "The Effect of Photoimmunotherapy Followed by Liposomal Daunorubicin in a Mixed Tumor Model: A Demonstration of the Super-Enhanced Permeability and Retention Effect after Photoimmunotherapy", MOLECULAR CANCER THERAPEUTICS, vol. 13, no. 2, 1 February 2014 (2014-02-01), pages 426-432, XP55337451, US ISSN: 1535-7163, DOI: 10.1158/1535-7163.MCT-13-0633TAKAHITO NAKAJIMA ET AL: "Improving the Efficacy of Photoimmunotherapy (PIT) using a Cocktail of Antibody Conjugates in a Multiple Antigen Tumor Model", THERANOSTICS, vol. 3, no. 6, 1 January 2013 (2013-01-01) , pages 357-365, XP55219807, AU ISSN: 1838-7640, DOI: 10.7150/thno.5908TADANOBU NAGAYA ET AL: "Near Infrared Photoimmunotherapy Targeting EGFR Positive Triple Negative Breast Cancer: Optimizing the Conjugate-Light Regimen", PLOS ONE, vol. 10, no. 8, 27 August 2015 (2015-08-27), page e0136829, XP55314754, DOI: 10.1371/journal.pone.0136829Ntc02422979: "Study of RM-1929 and Photoimmunotherapy in Patients With Recurrent Head and Neck Cancer", , 17 April 2015 (2015-04-17), XP055624966, Retrieved from the Internet: URL:https://clinicaltrials.gov/ct2/history /NCT02422979?V_1=View#StudyPageTop [retrieved on 2019-09-23]20213720.4382784620201214BIEL, Merrill2563 Delaware AvenueMendota Heights, MN 51158USMAKINGS, Lewis, R.337 Cerro StreetEncinitas, CA 92024USHEIM, Roger2131 Caminito Del BarcoDel Mar, CA 92014USGARCIA-GUZMAN, Miguel4076 Carmel Springs WaySan Diego, CA 92130USCHIN, Eileen, Sun9645 Easter WaySan Diego, CA 92121USYADAV, Deepak13129 Old West AvenueSan Diego, CA 92129USFONG, Jerry7700 Marker RoadSan Diego, CA 92130USRakuten Medical, Inc.101828189N412938EP11080 Roselle StreetSan Diego, CA 92121USJ A Kemp LLP10166966680 Turnmill StreetLondon EC1M 5QUGBALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTRUS201604764020160818enWO201703136720170223201708