ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................*J2.0.21 - 2999001/03344275CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120230412W173deBibliographieenBibliographyfrBibliographieEP16843105.4201609022018031620200407enenen201562214142 P20150903US201662310254 P20160318US201662344651 P20160602US201662344791 P20160602US2023041220231520180711201828202303082023102022092020230412202315A61K 31/337 20060101AFI20220823BHEP A61K 31/357 20060101ALI20220823BHEP A61K 31/7068 20060101ALI20220823BHEP A61K 38/12 20060101ALI20220823BHEP A61K 38/15 20060101ALI20220823BHEP A61K 38/21 20060101ALI20220823BHEP A61K 38/50 20060101ALI20220823BHEP A61K 45/06 20060101ALI20220823BHEP A61P 35/00 20060101ALI20220823BHEP A61K 31/436 20060101ALI20220823BHEP A61K 31/437 20060101ALI20220823BHEP A61K 31/44 20060101ALI20220823BHEP A61K 31/475 20060101ALI20220823BHEP A61K 31/506 20060101ALI20220823BHEP A61K 31/519 20060101ALI20220823BHEP A61K 31/553 20060101ALI20220823BHEP A61K 31/565 20060101ALI20220823BHEP A61K 31/573 20060101ALI20220823BHEP A61K 31/664 20060101ALI20220823BHEP A61K 31/706 20060101ALI20220823BHEP A61K 31/555 20060101ALI20220823BHEP A61K 31/357 20130101 LI20190322BHEP A61K2300/00 20130101 LI20190322BHEP A61K 31/337 20130101 LI20190322BHEP A61K2300/00 20130101 LI20190322BHEP A61K 31/7068 20130101 LI20190322BHEP A61K2300/00 20130101 LI20190322BHEP A61K 31/555 20130101 LI20190605BHEP A61K2300/00 20130101 LI20190605BHEP A61K 33/243 20190101 LI20190605BHEP A61K2300/00 20130101 LI20190605BHEP A61K 38/21 20130101 LI20170817BHEP A61K2300/00 20130101 LI20170817BHEP A61K 38/50 20130101 LI20170817BHEP A61K2300/00 20130101 LI20170817BHEP A61K 31/44 20130101 LI20190605BHEP A61K2300/00 20130101 LI20190605BHEP A61K 38/15 20130101 LI20171023BHEP A61K2300/00 20130101 LI20171023BHEP A61K 38/12 20130101 LI20171023BHEP A61K2300/00 20130101 LI20171023BHEP A61K 38/12 20130101 LI20170330BHEP A61K 38/21 20130101 LI20170817BHEP A61K 38/50 20130101 LI20170817BHEP A61K 45/06 20130101 LI20171023BHEP A61K 31/44 20130101 LI20170817BHEP C12Y 305/01001 20130101 LI20171023BHEP A61K 31/337 20130101 LI20190322BHEP A61K 31/357 20130101 LI20190322BHEP A61K 31/555 20130101 LI20190605BHEP A61K 33/243 20190101 LI20190605BHEP A61K 31/436 20130101 LI20170427BHEP A61K 31/437 20130101 LI20170427BHEP A61K 31/475 20130101 LI20170427BHEP A61K 31/506 20130101 LI20170427BHEP A61K 31/519 20130101 LI20170427BHEP A61K 31/553 20130101 LI20170427BHEP A61K 31/565 20130101 LI20170427BHEP A61K 31/573 20130101 LI20170427BHEP A61K 31/664 20130101 LI20170427BHEP A61K 31/706 20130101 LI20170427BHEP A61K 31/7068 20130101 LI20170427BHEP A61K 38/15 20130101 LI20170427BHEP A61P 35/00 20180101 LI20200327BHEP A61P 35/02 20180101 LI20200327BHEP A61P 43/00 20180101 LI20200331BHEP A61K 38/08 20130101 FI20201222RHEP dePEPTIDOMIMETISCHE MAKROZYKLEN UND VERWENDUNGEN DAVONenPEPTIDOMIMETIC MACROCYCLES AND USES THEREOFfrMACROCYCLES PEPTIDOMIMÉTIQUES ET LEURS UTILISATIONSWO-A1-2012/021874WO-A1-2012/021875WO-A1-2013/123266WO-A1-2016/049355WO-A1-2016/049359WO-A1-2016/154058WO-A2-2012/021876CHANG, Y. S. ET AL.: 'Stapled a-helical peptide drug development: A potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy' PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES vol. 110, no. 36, 2013, pages E3445 - E3454, XP055333079BROWN, C. J. ET AL.: 'Stapled peptides with improved potency and specificity that activate p53' ACS CHEMICAL BIOLOGY. vol. 8, no. 3, 2012, pages 506 - 512, XP055139125AL-LAZIKANI, B. ET AL.: 'Combinatorial drug therapy for cancer in the post- genomic era' NATURE BIOTECHNOLOGY vol. 30, no. 7, 2012, pages 679 - 692, XP055370881LI, F. ET AL.: 'Molecular-targeted agents combination therapy for cancer: Developments and potentials' INTERNATIONAL JOURNAL OF CANCER. vol. 134, no. 6, 01 January 2014, pages 1257 - 1269, XP055517584 DOI: 10.1002/IJC.2826120190329AIVADO, Manuel127 Magnolia DriveChester Springs, Pennsylvania 19425USGUERLAVAIS, Vincent43 Kenliworth RoadArlington, Massachusetts 02476USOLSON, Karen174 Lakeview AvenueWaltham, Massachusetts 02451USAileron Therapeutics, Inc.101984014P104318EP51285 Summer Street, Unit 101Boston, MA 02210USAvidity IP101660475Broers Building Hauser Forum 21 JJ Thomson AvenueCambridge CB3 0FAGBALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTRUS201605019420160902enWO201704099020170309201710