(19)
(11) EP 3 349 789 A2

(12)

(88) Date of publication A3:
23.03.2017

(43) Date of publication:
25.07.2018 Bulletin 2018/30

(21) Application number: 16847487.2

(22) Date of filing: 16.09.2016
(51) International Patent Classification (IPC): 
A61K 39/02(2006.01)
A61K 39/00(2006.01)
 A61K 48/00(2006.01)
(86) International application number:
PCT/US2016/052322
(87) International publication number:
WO 2017/049218 (23.03.2017 Gazette 2017/12)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 17.09.2015 US 201562219961 P

(71) Applicant: Advaxis, Inc.
Princeton, NJ 08540 (US)

(72) Inventors:
  • PETIT, Robert
    Newtown, Pennsylvania 18940 (US)
  • MAURO, David J.
    Washington Crossing, Pennsylvania 18977 (US)

(74) Representative: J A Kemp 
14 South Square Gray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) RECOMBINANT LISTERIA VACCINE STRAINS AND METHODS OF USING THE SAME IN CANCER IMMUNOTHERAPY