(19)
(11) EP 3 356 327 A1

(12)

(43) Date of publication:
08.08.2018 Bulletin 2018/32

(21) Application number: 16778644.1

(22) Date of filing: 29.09.2016
(51) International Patent Classification (IPC): 
C07D 209/48(2006.01)
C07C 317/26(2006.01)
C07C 49/84(2006.01)
 A61K 31/4035(2006.01)
C07C 49/80(2006.01)
A61P 35/00(2006.01)
(86) International application number:
PCT/US2016/054390
(87) International publication number:
WO 2017/059040 (06.04.2017 Gazette 2017/14)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 29.09.2015 US 201562234094 P

(71) Applicant: Pliva Hrvatska D.O.O.
10000 Zagreb (HR)

(72) Inventors:
  • TAMAS, Tivadar
    H-4034 (HU)
  • KORODI, Ferenc
    H-4028 (HU)
  • HAJKO, Janos
    H-4030 (HU)
  • NAGY, Renata
    H-5300 (HU)
  • PAAL, Tihamer
    4026 (HU)
  • TOTH, Miklos
    H-4033 (HU)
  • NEMETHNE RACZ, Csilla
    H-4031 (HU)

(74) Representative: D Young & Co LLP 
120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)

   


(54) PROCESSES FOR THE PREPARATION OF APREMILAST AND INTERMEDIATES THEREOF