(19)
(11) EP 3 371 328 A2

(12)

(88) Date of publication A3:
11.05.2017

(43) Date of publication:
12.09.2018 Bulletin 2018/37

(21) Application number: 16862915.2

(22) Date of filing: 02.11.2016
(51) International Patent Classification (IPC): 
C12Q 1/68(2018.01)
(86) International application number:
PCT/US2016/060186
(87) International publication number:
WO 2017/079352 (11.05.2017 Gazette 2017/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 04.11.2015 US 201562250796 P

(71) Applicant: Idera Pharmaceuticals, Inc.
Cambridge, MA 02139 (US)

(72) Inventors:
  • JIANG, Weiwen
    Winchester, MA 01890 (US)
  • PUTTA, Mallikarjuna R.
    Lexington, MA 02420 (US)
  • ZHU, Fu-Gang
    Bedford, MA 01730 (US)
  • DIMUZIO, Jillian M.
    Harleysville, PA 19438 (US)
  • BHAGAT, Lakshmi
    Framingham, MA 01702 (US)
  • AGRAWAL, Sudhir
    Shrewsbury, MA 01545 (US)

(74) Representative: Boult Wade Tennant LLP 
Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT
London WC1X 8BT (GB)

   


(54) COMPOSITIONS FOR INHIBITING NLRP3 GENE EXPRESSION AND USES THEREOF