(19)

(11)

EP 3 373 946 A1

(12)

(43) Date of publication: 19.09.2018 Bulletin 2018/38 (21) Application number: 16831945.7 (22) Date of filing: 09.11.2016

(51) International Patent Classification (IPC):  A61K 36/575(2006.01) A23L 3/3472(2006.01) A61K 8/97(2017.01) A61K 36/48(2006.01) A61Q 17/00(2006.01) (86) International application number: PCT/US2016/061102 (87) International publication number: WO 2017/083363 (18.05.2017 Gazette 2017/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 09.11.2015 US 201562252987 P 07.11.2016 US 201615345006 (71) Applicant: Unigen, Inc. Seattle, WA 98121 (US)	(72) Inventors: JIAO, Ping Newcastle, Washington 98059 (US) JIA, Qi Olympia, Washington 98502 (US) HONG, Mei Feng Seattle, Washington 98199 (US) KIM, Misun Seattle, Washington 98121 (US) (74) Representative: CSY Herts  Helios Court 1 Bishop Square Hatfield, Hertfordshire AL10 9NE Hatfield, Hertfordshire AL10 9NE (GB)