(19)
(11) EP 3 382 015 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
03.11.2021 Bulletin 2021/44

(45) Mention of the grant of the patent:
29.09.2021 Bulletin 2021/39

(21) Application number: 18167295.7

(22) Date of filing: 05.08.2011
(27) Previously filed application:
 05.08.2011 PCT/EP2011/063542
(51) International Patent Classification (IPC): 
C12N 9/10(2006.01)
C12P 7/64(2006.01)
C12N 15/81(2006.01)
(52) Cooperative Patent Classification (CPC):
Y02E 50/10; C12P 7/649; C12N 9/1029; C12N 15/81

(54)

METHODS AND PRODUCTS FOR PRODUCTION OF WAX ESTERS

VERFAHREN UND PRODUKTE ZUR HERSTELLUNG VON WACHSESTERN

PROCÉDÉS ET PRODUITS POUR LA PRODUCTION D'ESTERS DE CIRE


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 06.08.2010 US 40102610 P

(43) Date of publication of application:
03.10.2018 Bulletin 2018/40

(62) Application number of the earlier application in accordance with Art. 76 EPC:
11739100.3 / 2601292

(73) Proprietor: Melt&Marble AB
412 96 Göteborg (SE)

(72) Inventors:
  • NIELSEN, Jens
    411 28 Göteborg (SE)
  • SHI, Shuobo
    Beijing, 100029 (CN)

(74) Representative: Barker Brettell Sweden AB 
Östermalmsgatan 87B
114 59 Stockholm
114 59 Stockholm (SE)


(56) References cited: : 
WO-A2-2005/118814
US-A1- 2009 117 629
   
  • KALSCHEUER RAINER ET AL: "Synthesis of novel lipids in Saccharomyces cerevisiae by heterologous expression of an unspecific bacterial acyltransferase", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 70, no. 12, 1 December 2004 (2004-12-01), pages 7119-7125, XP002336520, ISSN: 0099-2240, DOI: 10.1128/AEM.70.12.7119-7125.2004
  • MICHELL B J ET AL: "ISOFORM-SPECIFIC PURIFICATIONS AND SUBSTRATE SPECIFICITY OF THE 5'-AMP-ACTIVATED PROTEIN KINASE", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, US, vol. 271, no. 45, 8 November 1996 (1996-11-08), pages 28445-28450, XP002907309, ISSN: 0021-9258, DOI: 10.1074/JBC.271.45.28445
  • SAERENS SOFIE M G ET AL: "The Saccharomyces cerevisiae EHT1 and EEB1 genes encode novel enzymes with medium-chain fatty acid ethyl ester synthesis and hydrolysis capacity", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC, US, vol. 281, no. 7, 1 February 2006 (2006-02-01), pages 4446-4456, XP002420348, ISSN: 0021-9258, DOI: 10.1074/JBC.M512028200
  • Susanne Mandrup ET AL: "Effect of heterologous expression of acyl-CoA-binding protein on acyl-CoA level and composition in yeast", Biochemical Journal (1993) 290, 1 January 1993 (1993-01-01), pages 369-374, XP055011525, Great Britain Retrieved from the Internet: URL:http://www.ncbi.nlm.nih.gov/pmc/articl es/PMC1132282/pdf/biochemj00116-0077.pdf [retrieved on 2011-11-08]
  • D. SORGER: "A Yeast Strain Lacking Lipid Particles Bears a Defect in Ergosterol Formation", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 279, no. 30, 1 January 2004 (2004-01-01), pages 31190-31196, XP055002110, ISSN: 0021-9258, DOI: 10.1074/jbc.M403251200
  • Pamela J Trotter: "THE GENETICS OF FATTY ACIDMETABOLISM IN SACCHAROMYCES CEREVISIAE", Annual Review of Nutrition, 1 January 2001 (2001-01-01), pages 97-119, XP055011474, United States DOI: http://dx.doi.org/10.1146%2Fannurev.nutr.2 1.1.97 Retrieved from the Internet: URL:http://www.annualreviews.org/doi/pdf/1 0.1146/annurev.nutr.21.1.97 [retrieved on 2011-11-08]
  • KALSCHEUER R ET AL: "Microdiesel: Escherichia coli engineered for fuel production", MICROBIOLOGY, SOCIETY FOR GENERAL MICROBIOLOGY, READING, GB, vol. 152, 1 January 2006 (2006-01-01), pages 2529-2536, XP007903430, ISSN: 1350-0872, DOI: 10.1099/MIC.0.29028-0
  • GUSTAFSSON C ET AL: "Codon bias and heterologous protein expression", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 22, no. 7, 1 July 2004 (2004-07-01), pages 346-353, XP004520507, ISSN: 0167-7799, DOI: 10.1016/J.TIBTECH.2004.04.006
  • S. SHI ET AL: "Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1", MBIO, vol. 5, no. 3, 6 May 2014 (2014-05-06), pages e01130-14, XP055289711, DOI: 10.1128/mBio.01130-14
   
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