LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY - Patent 3387150

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EP 3 387 150 A1

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(43)	Date of publication:
	17.10.2018 Bulletin 2018/42

(21)	Application number: 16820351.1

(22)	Date of filing: 09.12.2016

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International Patent Classification (IPC):

C12Q 1/68^(2018.01)

(86)	International application number:
	PCT/IB2016/057499

(87)	International publication number:
	WO 2017/098468 (15.06.2017 Gazette 2017/24)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	MA MD

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Priority:

09.12.2015 US 201562265099 P

(71)	Applicant: Novartis AG
	4056 Basel (CH)

(72)	Inventor:
	BEVERLY, Michael Cambridge, Massachusetts 02139 (US)

(74)	Representative: Masselink, Johannes Hendrikus Bernardus et al
	Novartis Pharma AG Patent Department 4002 Basel 4002 Basel (CH)

(54)	LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY