(19)
(11) EP 3 390 420 A1

(12)

(43) Date of publication:
24.10.2018 Bulletin 2018/43

(21) Application number: 16822412.9

(22) Date of filing: 15.12.2016
(51) International Patent Classification (IPC): 
C07F 15/00(2006.01)
C12Q 1/68(2018.01)
 A61K 33/24(2006.01)
G01N 33/543(2006.01)
(86) International application number:
PCT/EP2016/081166
(87) International publication number:
WO 2017/102934 (22.06.2017 Gazette 2017/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 15.12.2015 WO PCT/EP2015/307009

(71) Applicants:
  • Centre National de la Recherche Scientifique
    75016 Paris (FR)
  • Institut Curie
    75248 Paris Cedex 05 (FR)
  • The University Of Texas At Austin
    Austin, Texas 78712 (US)
  • Institut National de la Santé et de la Recherche Médicale
    75013 Paris (FR)

(72) Inventors:
  • RODRIGUEZ, Raphaël
    30210 Vers-Pont-du-Gard (FR)
  • ZACHARIOUDAKIS, Emmanouil
    91400 Orsay (FR)
  • KUNALINGAM, Lavaniya
    95200 Sarcelles (FR)
  • BARTOLI, Alexandra
    13013 Marseille (FR)
  • MILLER, Kyle
    Austin TX 78712 (US)
  • AGARWAL, Poonam
    Austin TX 78712 (US)

(74) Representative: Cabinet Becker et Associés 
25, rue Louis le Grand
75002 Paris
75002 Paris (FR)

   


(54) VISUAL DETECTION OF PLATINATED DNA LESIONS FROM A CLICKABLE CISPLATIN PROBE USED AS DIAGNOSTIC TOOL OR TO IDENTIFY SYNERGISTIC TREATMENTS