(19)
(11) EP 3 390 657 A1

(12)

(43) Date of publication:
24.10.2018 Bulletin 2018/43

(21) Application number: 16820524.3

(22) Date of filing: 15.12.2016
(51) International Patent Classification (IPC): 
C12Q 1/68(2018.01)
(86) International application number:
PCT/US2016/066901
(87) International publication number:
WO 2017/106481 (22.06.2017 Gazette 2017/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 17.12.2015 US 201562268961 P
29.09.2016 US 201662401591 P

(71) Applicant: Illumina, Inc.
San Diego, CA 92122 (US)

(72) Inventors:
  • TOUNG, Jonathan
    San Diego, CA 92122 (US)
  • LIU, Li
    San Diego, CA 92122 (US)
  • SHEN, Min-jui, Richard
    Rancho Santa Fe, CA 92067 (US)
  • ZHANG, Ruoyu
    Ithaca, NY 14850 (US)

(74) Representative: Dehns 
St. Brides House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)

   


(54) DISTINGUISHING METHYLATION LEVELS IN COMPLEX BIOLOGICAL SAMPLES