(19)
(11) EP 3 391 038 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
28.09.2022 Bulletin 2022/39

(45) Mention of the grant of the patent:
09.02.2022 Bulletin 2022/06

(21) Application number: 16861086.3

(22) Date of filing: 12.12.2016
(51) International Patent Classification (IPC): 
G01N 27/333(2006.01)
G01N 33/49(2006.01)
 G01N 33/62(2006.01)
(52) Cooperative Patent Classification (CPC):
G01N 27/3335; C12Q 1/58; G01N 33/49
(86) International application number:
PCT/EP2016/080607
(87) International publication number:
WO 2017/125208 (27.07.2017 Gazette 2017/30)

(54)

METHOD OF OPERATING A MIXED IONOPHORE ION-SELECTIVE ELECTRODE FOR THE IMPROVED DETECTION OF UREA IN BLOOD

VERFAHREN ZUM BETRIEB EINER IONENSELEKTIVEN ELEKTRODE MIT GEMISCHTEN IONOPHOREN ZUR VERBESSERTEN ERKENNUNG VON HARNSTOFF IN BLUT

PROCEDE D'UTILISATION D'UNE ÉLECTRODE SÉLECTIVE D'IONS PAR UN MÉLANGE D'IONOPHORES POUR LA DÉTECTION AMÉLIORÉE DE L'URÉE DANS LE SANG

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 18.12.2015 DK 201500818

(43) Date of publication of application:
24.10.2018 Bulletin 2018/43

(60) Divisional application:
22155426.4 / 4027137

(73) Proprietor: Radiometer Medical ApS
2700 Brønshøj (DK)

(72) Inventors:
  • KJAER, Thomas
    2765 Smoerum (DK)
  • MICHELSEN, Lone
    2720 Vanloese (DK)
  • SOERENSEN, Poul, Ravn
    1360 Copenhagen K (DK)
  • JAKOBSEN, Hans, Peter, Blaabjerg
    2610 Roedoevre (DK)

(74) Representative: Sverrisdóttir, Audur 
Radiometer Medical ApS Åkandevej 21
2700 Brønshøj
2700 Brønshøj (DK)


(56) References cited: : 
US-A- 4 762 594
US-A1- 2006 060 471
 US-A- 5 580 441
   
  • BAKKER E. ET AL.: "Ion-Selective Electrodes Based on Two Competitive Ionophores for Determining Effective Stability Constants of Ion-Carrier Complexes in Solvent Polymeric Membranes", ANAL. CHEM., vol. 70, 1998, pages 295-302, XP002770686,
  • LEE K. S. ET AL.: "Multiionophore-based solid-state potentiometric ion sensor as a cation detector for ion chromatography", SENSORS AND ACTUATORS B, vol. 20, 1994, pages 239-246, XP002770687,
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).