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EP 3 394 081 A1

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(43) Date of publication: 31.10.2018 Bulletin 2018/44 (21) Application number: 16714049.0 (22) Date of filing: 08.01.2016

(51) International Patent Classification (IPC):  C07J 9/00(2006.01) C07J 51/00(2006.01) A61P 1/16(2006.01) C07J 17/00(2006.01) A61K 31/575(2006.01) (86) International application number: PCT/US2016/012651 (87) International publication number: WO 2017/111979 (29.06.2017 Gazette 2017/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 22.12.2015 US 201514979005 (71) Applicant: Intercept Pharmaceuticals, Inc. New York, NY 10011 (US)

(72) Inventors: STEINER, André 83064 Raubling (DE) WAENERLUND POULSEN, Heidi 4600 Køge (DK) JOLIBOIS, Emilie Cambridge CB4 0WE (GB) REWOLINSKI, Melissa San Diego, CA 92122 (US) GROSS, Ralf 83064 Raubling (DE) SHARP, Emma Cambridge CB4 0WE (GB) DUBAS-FISHER, Fiona Cambridge CB4 0WE (GB) EBERLIN, Alex Cambridge CB4 0WE (GB) (74) Representative: Cooley (UK) LLP  Dashwood 69 Old Broad Street London EC2M 1QS London EC2M 1QS (GB)