(19)

(11)

EP 3 397 641 A1

(12)

(43) Date of publication: 07.11.2018 Bulletin 2018/45 (21) Application number: 16826889.4 (22) Date of filing: 29.12.2016

(51) International Patent Classification (IPC):  C07D 491/052(2006.01) A61K 31/519(2006.01) A61P 37/00(2006.01) C07D 495/04(2006.01) A61P 29/00(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2016/069124 (87) International publication number: WO 2017/117355 (06.07.2017 Gazette 2017/27)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 29.12.2015 US 201562272408 P (71) Applicant: Immunetarget, Inc. San Diego, CA 92121 (US)	(72) Inventors: OUK, Samedy San Diego, CA 92130 (US) LIOU, Hsiou-Chi New York, NY 10128 (US) (74) Representative: Goodfellow, Hugh Robin  Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA London WC1B 5HA (GB)