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(11)

EP 3 402 878 A1

(12)

(43) Date of publication: 21.11.2018 Bulletin 2018/47 (21) Application number: 16704501.2 (22) Date of filing: 11.01.2016

(51) International Patent Classification (IPC):  C12N 7/00(2006.01) A61K 39/215(2006.01) C12N 7/08(2006.01) (86) International application number: PCT/US2016/012899 (87) International publication number: WO 2017/123201 (20.07.2017 Gazette 2017/29)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (71) Applicant: Zoetis Services LLC Parsippany, NJ 07054 (US)

(72) Inventors: CABANA SUMSI, Marta Florham Park, NJ 07932 (US) BALASCH SANUY, Monica Florham Park, NJ 07932 (US) PLAJA DILMÉ, Laia Florham Park, NJ 07932 (US) URNIZA HOSTENCH, Alicia Florham Park, NJ 07932 (US) DOMINOWSKI, Paul, J. Kalamazoo, MI 49007 (US) CALVERT, Jay, Gregory Kalamazoo, MI 49007 (US) (74) Representative: Mannion, Sally Kim  Zoetis European Patent Department Walton Oaks, Dorking Road Tadworth Surrey KT20 7NS Tadworth Surrey KT20 7NS (GB)