(19)
(11) EP 3 411 051 A2

(12)

(88) Date of publication A3:
08.09.2017

(43) Date of publication:
12.12.2018 Bulletin 2018/50

(21) Application number: 17705544.9

(22) Date of filing: 03.02.2017
(51) International Patent Classification (IPC): 
A61K 35/74(2015.01)
(86) International application number:
PCT/US2017/016603
(87) International publication number:
WO 2017/136792 (10.08.2017 Gazette 2017/32)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 04.02.2016 US 201662291461 P
04.02.2016 US 201662291468 P
04.02.2016 US 201662291470 P
02.03.2016 WO PCT/US2016/020530
13.05.2016 WO PCT/US2016/032565
08.06.2016 US 201662347508 P
08.06.2016 US 201662347576 P
10.06.2016 US 201662348620 P
24.06.2016 WO PCT/US2016/039444
24.06.2016 US 201662354682 P
15.07.2016 US 201662362954 P
08.09.2016 US 201662385235 P
08.09.2016 US 201615260319
08.09.2016 WO PCT/US2016/050836
16.11.2016 US 201662423170 P
28.12.2016 US 201662439871 P
28.12.2016 WO PCT/US2016/069052

(71) Applicant: Synlogic Operating Company, Inc.
Cambridge, MA 02142 (US)

(72) Inventors:
  • MILLER, Paul, F.
    Salem CT 06420 (US)
  • ISABELLA, Vincent, M.
    Cambridge MA 02139 (US)
  • KOTULA, Jonathan, W.
    Somerville MA 02143 (US)
  • FALB, Dean
    Sherborn MA 01770 (US)
  • FISHER, Adam, B.
    Cambridge MA 02139 (US)
  • MILLET, Yves
    Newton MA 02460 (US)
  • LI, Ning
    Winchester MA 01890 (US)

(74) Representative: Ford, Hazel et al
Mathys & Squire LLP The Shard 32 London Bridge Street
London SE1 9SG
London SE1 9SG (GB)

   


(54) BACTERIA ENGINEERED TO TREAT DISEASES THAT BENEFIT FROM REDUCED GUT INFLAMMATION AND/OR TIGHTENED GUT MUCOSAL BARRIER