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EP 3 411 068 A2

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(88) Date of publication A3: 28.09.2017 (43) Date of publication: 12.12.2018 Bulletin 2018/50 (21) Application number: 17748163.7 (22) Date of filing: 02.02.2017

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/28(2006.01) C07K 16/22(2006.01) (86) International application number: PCT/US2017/016230 (87) International publication number: WO 2017/136562 (10.08.2017 Gazette 2017/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 02.02.2016 US 201662290350 P (71) Applicant: Kadmon Corporation, LLC New York, NY 10016 (US)	(72) Inventors: ZHU, Zhenping Woodcliff Lake, NJ 07677 (US) LU, Dan Montvale, NJ 07645 (US) (74) Representative: Pohlman, Sandra M.  df-mp Dörries Frank-Molnia & Pohlman Patentanwälte Rechtsanwälte PartG mbB Theatinerstrasse 16 80333 München 80333 München (DE)