(19)
(11) EP 3 419 618 A1

(12)

(43) Date of publication:
02.01.2019 Bulletin 2019/01

(21) Application number: 16891868.8

(22) Date of filing: 15.07.2016
(51) International Patent Classification (IPC): 
A61K 31/405(2006.01)
A61P 35/00(2006.01)
C07K 16/46(2006.01)
 A61K 31/519(2006.01)
C07K 16/28(2006.01)
(86) International application number:
PCT/US2016/042591
(87) International publication number:
WO 2017/146767 (31.08.2017 Gazette 2017/35)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 26.02.2016 WO PCT/US2016/019953

(71) Applicant: iCell Gene Therapeutics, LLC
Stony Brook, NY 11790 (US)

(72) Inventors:
  • MA, Yupo
    Stony Brook, NY 11790 (US)
  • PINZ, Kevin
    Stony Brook, NY 11790 (US)
  • JIANG, Xun
    Stony Brook, NY 11790 (US)
  • WADA, Masayuki
    Stony Brook, NY 11790 (US)
  • CHEN, Kevin
    Stony Brook, NY 11790 (US)

(74) Representative: V.O. 
P.O. Box 87930 Carnegieplein 5
2508 DH Den Haag
2508 DH Den Haag (NL)

   


(54) CHIMERIC ANTIGEN RECEPTORS (CARS) TARGETING HEMATOLOGIC MALIGNANCIES, COMPOSITIONS AND METHODS OF USE THEREOF