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(11)

EP 3 423 094 A1

(12)

(43) Date of publication: 09.01.2019 Bulletin 2019/02 (21) Application number: 16891935.5 (22) Date of filing: 29.02.2016

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61P 3/08(2006.01) A61P 3/04(2006.01) A61P 3/10(2006.01) (86) International application number: PCT/CN2016/074809 (87) International publication number: WO 2017/147742 (08.09.2017 Gazette 2017/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (71) Applicant: Eli Lilly and Company Indianapolis, IN 46285 (US)	(72) Inventor: WU, Xinle Indianapolis, Indiana 46206-6288 (US) (74) Representative: Bassinder, Emma Marie et al Eli Lilly and Company Limited European Patent Operations Erl Wood Manor Sunninghill Road Windlesham, Surrey GU20 6PH Windlesham, Surrey GU20 6PH (GB)