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(11)

EP 3 442 638 A2

(12)

(88) Date of publication A3: 22.02.2018 (43) Date of publication: 20.02.2019 Bulletin 2019/08 (21) Application number: 16908351.6 (22) Date of filing: 13.12.2016

(51) International Patent Classification (IPC):  A61M 25/00(2006.01) A61B 34/20(2016.01) A61M 1/12(2006.01) A61M 1/16(2006.01) A61M 25/09(2006.01) (86) International application number: PCT/US2016/066336 (87) International publication number: WO 2018/009241 (11.01.2018 Gazette 2018/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 14.04.2016 US 201662322293 P 24.10.2016 US 201615332741 (71) Applicant: The Regents of the University of California Oakland, CA 94607 (US)	(72) Inventor: ARDEHALI, Abbas Los Angeles, CA 90049 (US) (74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB  Ganghoferstraße 68 B 80339 München 80339 München (DE)