(19)
(11) EP 3 445 868 A1

(12)

(43) Date of publication:
27.02.2019 Bulletin 2019/09

(21) Application number: 17717204.6

(22) Date of filing: 19.04.2017
(51) International Patent Classification (IPC): 
C12Q 1/68(2018.01)
(86) International application number:
PCT/EP2017/059303
(87) International publication number:
WO 2017/182529 (26.10.2017 Gazette 2017/43)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 19.04.2016 EP 16166083
11.01.2017 EP 17305038

(71) Applicants:
  • Institut National de la Santé et de la Recherche Médicale (INSERM)
    75013 Paris (FR)
  • Université Paris Descartes
    75006 Paris (FR)
  • Centre Hospitalier Sainte-Anne
    75014 Paris (FR)

(72) Inventors:
  • KREBS, Marie-Odile
    75014 Paris (FR)
  • KEBIR, Oussama
    75014 Paris (FR)
  • CHAUMETTE, Boris
    75014 Paris (FR)

(74) Representative: Lavoix 
2, place d'Estienne d'Orves
75441 Paris Cedex 09
75441 Paris Cedex 09 (FR)

   


(54) METHYLOMIC AND TRANSCRIPTOMIC CHANGES DURING CONVERSION TO PSYCHOSIS