| (19) |
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(11) |
EP 3 446 712 A8 |
| (12) |
CORRECTED EUROPEAN PATENT APPLICATION |
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Note: Bibliography reflects the latest situation |
| (15) |
Correction information: |
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Corrected version no 1 (W1 A1) |
| (48) |
Corrigendum issued on: |
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10.04.2019 Bulletin 2019/15 |
| (43) |
Date of publication: |
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27.02.2019 Bulletin 2019/09 |
| (22) |
Date of filing: 14.03.2014 |
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| (51) |
International Patent Classification (IPC):
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| (84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
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Designated Extension States: |
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BA ME |
| (30) |
Priority: |
14.03.2013 US 201361783663 P
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| (62) |
Application number of the earlier application in accordance with Art. 76 EPC: |
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14718284.4 / 2968586 |
| (71) |
Applicants: |
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- Translate Bio, Inc.
Lexington, MA 02421 (US)
- Ethris GmbH
82152 Planegg (DE)
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| (72) |
Inventors: |
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- HEARTLEIN, Michael
Lexington, MA 02421 (US)
- GUILD, Braydon Charles
Concord, MA 01742 (US)
- DEROSA, Frank
Lexington, MA 02421 (US)
- RUDOLPH, Carsten
82152 Krailing (DE)
- PLANK, Christian
82234 Wessling (DE)
- SMITH, Lianne
Lexington, MA 02421 (US)
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| (74) |
Representative: Goodfellow, Hugh Robin |
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Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA
London WC1B 5HA (GB) |
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Remarks: |
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This application was filed on 24-07-2018 as a divisional application to the application
mentioned under INID code 62. |
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| (54) |
CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES |
(57) Materials, formulations, production methods, and methods for delivery of CFTR mRNA
for induction of CFTR expression, including in the mammalian lung are provided. The
present invention is particularly useful for treating cystic fibrosis.