(19)
(11) EP 3 448 392 A1

(12)

(43) Date of publication:
06.03.2019 Bulletin 2019/10

(21) Application number: 17790519.7

(22) Date of filing: 28.04.2017
(51) International Patent Classification (IPC): 
A61K 31/70(2006.01)
A61K 31/7076(2006.01)
C07H 19/04(2006.01)
 A61K 31/7072(2006.01)
C07H 19/02(2006.01)
C07H 19/056(2006.01)
(86) International application number:
PCT/US2017/030080
(87) International publication number:
WO 2017/189978 (02.11.2017 Gazette 2017/44)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 28.04.2016 US 201662328857 P

(71) Applicant: Emory University
Atlanta, GA 30322 (US)

(72) Inventors:
  • BLUEMLING, Gregory
    Decatur Georgia 30033 (US)
  • DE LA ROSA, Abel
    Alpharetta Georgia 30005 (US)
  • PAINTER, George
    Atlanta Georgia 30322 (US)
  • KUIPER, Damien
    Atlanta Georgia 30345 (US)
  • KOLYKHALOV, Alexander
    Atlanta Georgia 30322 (US)

(74) Representative: Dehns 
St. Brides House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)

   


(54) ALKYNE CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO