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EP 3 452 033 A1

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(43) Date of publication: 13.03.2019 Bulletin 2019/11 (21) Application number: 17793224.1 (22) Date of filing: 03.05.2017

(51) International Patent Classification (IPC):  A61K 31/196(2006.01) A61K 31/4709(2006.01) A61K 31/593(2006.01) (86) International application number: PCT/US2017/030772 (87) International publication number: WO 2017/192675 (09.11.2017 Gazette 2017/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 06.05.2016 US 201615148574 10.06.2016 US 201615178812 (71) Applicant: Imprimis Pharmaceuticals Inc. San Diego, CA 92130 (US)

(72) Inventors: WILEY, William Chagrin Falls, Ohio 44022 (US) DILZER, Richard Long Valley, New Jersey 07853 (US) SAADEH, Dennis Elias Irvine, California 92618 (US) LIEGNER, Jeffrey T. Newton, New Jersey 07860 (US) KAROLCHYK, John Scott Lake Hopatcong, New Jersey 07849 (US) COVALESKY, Bernard Randolph, New Jersey 07869 (US) PETERS, Kallan Flemington, New Jersey 08822 (US) (74) Representative: Gill, Siân Victoria et al Venner Shipley LLP 200 Aldersgate London EC1A 4HD London EC1A 4HD (GB)