ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................JBDM Ver 2.0.24 - 2999001/03460064CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120240320W173deBibliographieenBibliographyfrBibliographieEP18183738.6201203122019092720200707enenen201161471166 P20110403US201161471584 P20110404US2024032020241220190327201913202402072024062023082120240320202412C12N 15/87 20060101AFI20190108BHEP C12N 15/11 20060101ALI20190108BHEP A61K 48/00 20060101ALI20190108BHEP A61P 43/00 20060101ALI20190108BHEP A61P 35/00 20060101ALI20190108BHEP A61K 31/7115 20060101ALI20190108BHEP A61K 31/4745 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 31/555 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 31/519 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 31/517 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 31/7115 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 31/7068 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 31/513 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A61K 33/24 20130101 LI20141020BHEP A61K2300/00 20130101 LI20141020BHEP A01K 67/0276 20130101 LI20130819BHEP A61K 48/005 20130101 LI20130819BHEP C12N 15/111 20130101 LI20130820BHEP A01K2207/05 20130101 LA20130819BHEP A01K2217/075 20130101 LA20130819BHEP A01K2227/105 20130101 LA20130819BHEP A01K2267/03 20130101 LA20130819BHEP A01K2267/0393 20130101 LA20130819BHEP C12N2310/11 20130101 LA20130820BHEP C12N2310/14 20130101 LA20130820BHEP C12N2800/30 20130101 LA20130819BHEP A61K 31/7115 20130101 LI20141008BHEP A61K 31/4745 20130101 LI20141020BHEP A61K 31/513 20130101 LI20141020BHEP A61K 31/517 20130101 LI20141020BHEP A61K 31/519 20130101 LI20141020BHEP A61K 31/555 20130101 LI20141020BHEP A61K 31/7068 20130101 LI20141020BHEP A61L 31/10 20130101 LI20141201BHEP A61L 31/16 20130101 LI20141201BHEP A61L2300/258 20130101 LA20141201BHEP A61K 38/1866 20130101 FI20140306BHEP A61P 1/18 20180101 LI20200318BHEP A61P 11/00 20180101 LI20200318BHEP A61P 13/12 20180101 LI20200319BHEP A61P 21/00 20180101 LI20200320BHEP A61P 21/04 20180101 LI20200320BHEP A61P 29/00 20180101 LI20200324BHEP A61P 35/00 20180101 LI20200327BHEP A61P 37/02 20180101 LI20200331BHEP A61P 37/06 20180101 LI20200331BHEP A61P 43/00 20180101 LI20200331BHEP A61P 9/00 20180101 LI20200331BHEP A61P 9/04 20180101 LI20200331BHEP A61P 9/06 20180101 LI20200331BHEP A61P 9/10 20180101 LI20200331BHEP A61P 9/12 20180101 LI20200331BHEP A61K 33/243 20190101 LI20210429RHEP deEFFIZIENTE IN-VIVO-PROTEINEXPRESSION MITTELS MODIFIZIERTER RNA (MOD-RNA)enEFFICIENT PROTEIN EXPRESSION IN VIVO USING MODIFIED RNA (MOD-RNA)frEXPRESSION PROTÉIQUE EFFICACE IN VIVO À L'AIDE D'ARN MODIFIÉ (MOD-ARN)WO-A1-2009/127230WO-A2-2007/024708WO-A2-2010/144678CA-A1- 2 769 670LIOR ZANGI ET AL: "Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction", NATURE BIOTECHNOLOGY, vol. 31, no. 10, 1 October 2013 (2013-10-01), pages 898-907, XP055145576, ISSN: 1087-0156, DOI: 10.1038/nbt.2682KATHY O. LUI ET AL: "Cardiovascular regenerative therapeutics via synthetic paracrine factor modified mRNA", STEM CELL RESEARCH, vol. 13, no. 3, 1 November 2014 (2014-11-01), pages 693-704, XP055532693, NL ISSN: 1873-5061, DOI: 10.1016/j.scr.2014.06.00712767300.2269466020120312CHIEN, Kenneth R.17 Saville StreetCambridge, MA 02138USPTASZEK, Leon M.133 Woodcliff RoadNewton, MA 02461USLUI, Oi Lan330 Tremont Street Room B604Boston, MA 02114USZANGI, Lior110 Est End Avneue, Apt. 8CNew York, NY 10028USEBINA, Wataru304 E 41st Street Apt. 804ANew York, New York 10017USROSSI, Derrick J.167 Lake AvenueNewton, MA 02459USThe General Hospital Corporation d/b/a Massachusetts General Hospital100236023P33448EPA/LK55 Fruit StreetBoston, MA 02114USThe Children's Medical Center Corporation102031956P33448EPA/LK300 Longwood AvenueBoston, MA 02115USKehoe, Laura Ellenet al101165317Keltie LLP No.1 London BridgeLondon SE1 9BAGBALATBEBGCHCYCZDEDKEEESFIFRGBGRHRHUIEISITLILTLULVMCMKMTNLNOPLPTRORSSESISKSMTR