(19)
(11) EP 3 463 290 A1

(12)

(43) Date of publication:
10.04.2019 Bulletin 2019/15

(21) Application number: 17810720.7

(22) Date of filing: 26.05.2017
(51) International Patent Classification (IPC): 
A61K 9/00(2006.01)
A61K 45/06(2006.01)
C12N 7/00(2006.01)
 A61K 35/12(2015.01)
A61K 48/00(2006.01)
C12N 9/22(2006.01)
(86) International application number:
PCT/US2017/034763
(87) International publication number:
WO 2017/213896 (14.12.2017 Gazette 2017/50)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 03.06.2016 US 201662345549 P
14.09.2016 US 201662394334 P

(71) Applicant: Temple University - Of The Commonwealth System of Higher Education
Philadelphia, PA 19122 (US)

(72) Inventors:
  • KHALILI, Kamel
    Bala Cynwyd PA 19004 (US)
  • HU, Wenhui
    Cherry Hill NJ 08003 (US)
  • KAMINSKI, Rafal
    Philadelphia PA 19134 (US)
  • MALCOLM, Thomas
    Bedminster NJ 07921 (US)

(74) Representative: HGF Limited 
Saviour House 9 St. Saviourgate
York YO1 8NQ
York YO1 8NQ (GB)

   


(54) NEGATIVE FEEDBACK REGULATION OF HIV-1 BY GENE EDITING STRATEGY