(19)
(11) EP 3 466 483 A8

(12) CORRECTED EUROPEAN PATENT APPLICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 A1)

(48) Corrigendum issued on:
04.03.2020 Bulletin 2020/10

(43) Date of publication:
10.04.2019 Bulletin 2019/15

(21) Application number: 18188950.2

(22) Date of filing: 08.03.2005
(51) International Patent Classification (IPC): 
A61N 1/32(2006.01)
A61N 1/30(2006.01)
 A61N 1/08(2006.01)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU MC NL PL PT RO SE SI SK TR

(30) Priority: 08.03.2004 US 551679 P

(62) Application number of the earlier application in accordance with Art. 76 EPC:
15165174.2 / 2929909
05725237.1 / 1729848

(71) Applicant: Ichor Medical Systems, Inc.
San Diego, CA 92121 (US)

(72) Inventors:
  • MASTERSON, Steven P.
    Encinitas, CA 92024 (US)
  • HANNAMAN, Andrew W.
    San Diego, CA 92130 (US)
  • BERNARD, Robert M.
    Rancho Santa Fe, CA 92067 (US)

(74) Representative: Wichmann, Hendrik 
Wuesthoff & Wuesthoff Patentanwälte PartG mbB Schweigerstraße 2
81541 München
81541 München (DE)

 
Remarks:
This application was filed on 14.08.2018 as a divisional application to the application mentioned under INID code 62.
Remarks:
Claims filed after the date of filing of the application / after the date of receipt of the divisional application (Rule 68(4) EPC).
 


(54) IMPROVED APPARATUS FOR ELECTRICALLY MEDIATED DELIVERY OF THERAPEUTIC AGENTS


(57) Apparatus for the delivery of an electrical field which facilitates the intracellular delivery of a therapeutic agent to a predetermined site within the tissue of a patient. The apparatus will comprise a plurality of penetrating electrodes arranged in a predetermined spatial relationship, each electrode with a cross sectional area contributing to the total cross sectional area of all electrodes, and structural means incorporating an inanimate source of energy operatively connected to the plurality of electrodes for deploying the electrodes, wherein the source of energy is sufficient to impart a force of at least 1000 pounds per square inch (0.7 kilogram per square millimeter) of total cross sectional area of all electrodes at the initiation of the deployment of the electrodes. The apparatus will also comprise means for generating an electrical field which facilitates the intracellular delivery of a therapeutic agent, which means is operatively connected to said electrodes a least in their deployed state.