(19)

(11)

EP 3 468 987 A2

(12)

(88) Date of publication A3: 18.01.2018 (43) Date of publication: 17.04.2019 Bulletin 2019/16 (21) Application number: 17731089.3 (22) Date of filing: 08.06.2017

(51) International Patent Classification (IPC):  C07K 14/605(2006.01) C12Q 1/37(2006.01) A61K 38/26(2006.01) (86) International application number: PCT/EP2017/063905 (87) International publication number: WO 2017/211922 (14.12.2017 Gazette 2017/50)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 09.06.2016 US 201662347693 P (71) Applicant: Medimmune Limited Cambridge, Cambridgeshire CB21 6GH (GB)	(72) Inventor: BEDNAREK, Maria, A Cambridge Cambridgeshire CB21 6GH (GB) (74) Representative: AstraZeneca  Milstein Building Granta Park Cambridge CB21 6GH Cambridge CB21 6GH (GB)