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EP 3 484 359 A1

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(43) Date of publication: 22.05.2019 Bulletin 2019/21 (21) Application number: 17831723.6 (22) Date of filing: 18.07.2017

(51) International Patent Classification (IPC):  A61B 5/05(2006.01) A61B 18/14(2006.01) A61N 1/40(2006.01) G21K 1/00(2006.01) A61B 5/055(2006.01) A61B 18/18(2006.01) A61N 5/10(2006.01) (86) International application number: PCT/US2017/042676 (87) International publication number: WO 2018/017618 (25.01.2018 Gazette 2018/04)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 18.07.2016 US 201662363795 P (71) Applicant: Neotherma Oncology, Inc. Wichita, Kansas 67201 (US)	(72) Inventors: ANDERSON, JR., Charles Eric Lee'sSummit Missouri 64081 (US) WANDELL, Michael George Seattle Washington 98116 (US) JONES, Randall Wayne Omaha Nebraska 68136 (US) (74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB  Siebertstrasse 3 81675 München 81675 München (DE)