| (84) |
Designated Contracting States: |
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AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
29.07.2016 US 201662368822 P
31.03.2017 US 201762479671 P
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| (43) |
Date of publication of application: |
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05.06.2019 Bulletin 2019/23 |
| (60) |
Divisional application: |
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24176375.4 |
| (73) |
Proprietor: Ohio State Innovation Foundation |
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Columbus, OH 43201 (US) |
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| (72) |
Inventors: |
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- KAUR, Balveen
Houston
Texas 77030 (US)
- RUSSELL, Luke
Rochester
Minnesota 55906 (US)
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| (74) |
Representative: Creek, Isobel Clare |
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The IP Asset Partnership Limited
Prama House
267 Banbury Road
Oxford OX2 7HT
Oxford OX2 7HT (GB) |
| (56) |
References cited: :
WO-A1-2013/169388
US-A1- 2008 292 592
US-A1- 2013 065 952
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US-A1- 2007 092 968
US-A1- 2012 039 861
US-A1- 2014 065 694
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- ZHONG ET AL: "Mannan-modified Ad5-PTEN treatment combined with docetaxel improves
the therapeutic effect in H22 tumor-bearing mice", INTERNATIONAL JOURNAL OF NANOMEDICINE,
1 September 2012 (2012-09-01), pages 5039, XP055661684, DOI: 10.2147/IJN.S34022
- MIAO DING ET AL: "Prostate Cancer-Specific and Potent Antitumor Effect of a DD3-Controlled
Oncolytic Virus Harboring the PTEN Gene", PLOS ONE, vol. 7, no. 4, 11 April 2012 (2012-04-11),
pages e35153, XP055661553, DOI: 10.1371/journal.pone.0035153
- LUKE RUSSELL ET AL: "Abstract 601: Oncolytic and immune effects of RAPTOR: a novel
oncolytic Herpes Simplex Virus 1 expressing PTEN-L for brain tumor therapy", CANCER
RESEARCH, vol. 77, no. Suppl. 13, 1 April 2017 (2017-04-01), pages 601, XP055661567,
DOI: 10.1158/1538-7445.AM2017-601
- PALIAN, B: "MAF1 is a Novel Target of the Tumor Suppressor PTEN and a Negative Regulator
of Lipid Metabolism", THESIS, UNIVERSITY OF SOUTHERN CALIFORNIA, 13 June 2012 (2012-06-13),
pages 1 - 65, XP055457973, Retrieved from the Internet <URL:http://cdm15799.contentdm.oclc.org/cdm/ref/collection/p15799coll3/id/48553>
[retrieved on 20170913]
- GEORGE ET AL.: "Loss of PTEN Is Associated with Resistance to Anti-PD-1 Checkpoint
Blockade Therapy in Metastatic Uterine Leiomyosarcoma", IMMUNITY, vol. 46, no. 2,
21 February 2017 (2017-02-21), pages 197 - 204, XP029929852
- "Catalog no. V810-20", THERMOFISHER SCIENTIFIC, 9 November 2010 (2010-11-09), pages
1 - 23, XP055457982, Retrieved from the Internet <URL:https://assets.thermofisher.com/TFS-Assets/LSG/manuals/pcdna3_1v5his_man.pdf>
[retrieved on 20170913]
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