(19)

(11)

EP 3 490 614 A1

(12)

(43) Date of publication: 05.06.2019 Bulletin 2019/23 (21) Application number: 17748889.7 (22) Date of filing: 27.07.2017

(51) International Patent Classification (IPC):  A61K 49/04(2006.01) C07K 7/06(2006.01) (86) International application number: PCT/GB2017/052203 (87) International publication number: WO 2018/020262 (01.02.2018 Gazette 2018/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 28.07.2016 GB 201613035 (71) Applicant: Oxford University Innovation Limited Botley Oxford OX2 0JB (GB)	(72) Inventors: LIM, Ngee Han Headington Oxford OX3 7FY (GB) FOWKES, Milan Mrazek Headington Oxford OX3 7FY (GB) (74) Representative: HGF Limited  4th Floor Merchant Exchange 17-19 Whitworth Street West Manchester M1 5WG Manchester M1 5WG (GB)