(19)
(11) EP 3 495 358 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
08.06.2022 Bulletin 2022/23

(45) Mention of the grant of the patent:
27.04.2022 Bulletin 2022/17

(21) Application number: 18197550.9

(22) Date of filing: 07.11.2013
(51) International Patent Classification (IPC): 
C07D 403/12(2006.01)
C07D 237/24(2006.01)
C07D 413/14(2006.01)
C07D 413/12(2006.01)
C07D 417/14(2006.01)
A61K 31/50(2006.01)
A61K 31/506(2006.01)
A61P 29/00(2006.01)
C07D 401/12(2006.01)
C07D 401/14(2006.01)
C07D 403/14(2006.01)
C07D 417/12(2006.01)
A61K 31/501(2006.01)
A61K 31/5377(2006.01)
A61K 31/513(2006.01)
A61P 37/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 403/12; C07D 401/14; C07D 413/14; C07D 401/12; C07D 237/24; C07D 403/14; C07D 413/12; C07D 417/12; C07D 417/14; A61P 1/00; A61P 1/04; A61P 13/12; A61P 17/06; A61P 19/02; A61P 29/00; A61P 37/00; A61P 37/02; A61P 37/06; A61P 43/00; A61P 7/00

(54)

AMIDE-SUBSTITUTED HETEROCYCLIC COMPOUNDS USEFUL AS MODULATORS OF IL-12, IL-23 AND/OR IFN ALPHA RESPONSES

AMIDSUBSTITUIERTE HETEROCYCLISCHE VERBINDUNGEN ALS MODULATOREN VON IL-12-, IL-23- UND/ODER IFN-ALPHA-REAKTIONEN

COMPOSÉS HÉTÉROCYCLIQUES SUBSTITUÉS PAR DES GROUPEMENTS AMIDES UTILES EN TANT QUE MODULATEURS D'IL-12, IL-23 ET/OU DE RÉPONSES IFN ALPHA


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 08.11.2012 US 201261723840 P

(43) Date of publication of application:
12.06.2019 Bulletin 2019/24

(60) Divisional application:
22165094.8

(62) Application number of the earlier application in accordance with Art. 76 EPC:
13811640.5 / 2922846

(73) Proprietor: Bristol-Myers Squibb Company
Princeton, NJ 08543 (US)

(72) Inventors:
  • MOSLIN, Ryan M.
    Princeton, NJ 08543 (US)
  • WEINSTEIN, David S.
    Princeton, NJ 08543 (US)
  • WROBLESKI, Stephen T.
    Princeton, NJ 08543 (US)
  • TOKARSKI, John S.
    Princeton, NJ 08543 (US)
  • KUMAR, Amit
    Bangalore 560099 Karnataka (IN)
  • BATT, Douglas G.
    Princeton, NJ 08543 (US)
  • LIN, Shuqun
    Princeton, NJ 08543 (US)
  • LIU, Chunjian
    Princeton, NJ 08543 (US)
  • SPERGEL, Steven H.
    Princeton, NJ 08543 (US)
  • ZHANG, Yanlei
    Princeton, NJ 08543 (US)

(74) Representative: Mewburn Ellis LLP 
Aurora Building Counterslip
Bristol BS1 6BX
Bristol BS1 6BX (GB)


(56) References cited: : 
EP-A1- 1 184 376
WO-A1-2014/074661
WO-A1-00/76980
WO-A1-2018/183649
   
       
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).