(19)

(11)

EP 3 500 261 A1

(12)

(43) Date of publication: 26.06.2019 Bulletin 2019/26 (21) Application number: 17841883.6 (22) Date of filing: 10.08.2017

(51) International Patent Classification (IPC):  A61K 31/485(2006.01) A61K 9/00(2006.01) A61K 47/18(2017.01) (86) International application number: PCT/US2017/046198 (87) International publication number: WO 2018/034920 (22.02.2018 Gazette 2018/08)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 17.08.2016 US 201615238909 22.05.2017 US 201715601331 (71) Applicant: Insys Development Company, Inc. Chandler, AZ 85286 (US)	(72) Inventors: AMANCHA, Kiran Chandler AZ 85286 (US) CHILAMPALLI, Shivani Chandler AZ 85286 (US) POTTA, Thrimoorthy Chandler AZ 85286 (US) YAN, Ningxin Chandler AZ 85286 (US) GOSKONDA, Venkat, R. Chandler AZ 85286 (US) NARAYANAN, Eshwaran Chandler, AZ 85286 (US) (74) Representative: Elkington and Fife LLP  Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR Sevenoaks, Kent TN13 1XR (GB)