(19)

(11)

EP 3 506 889 A1

(12)

(43) Date of publication: 10.07.2019 Bulletin 2019/28 (21) Application number: 17754232.1 (22) Date of filing: 01.08.2017

(51) International Patent Classification (IPC):  A61K 9/70(2006.01) A61K 31/137(2006.01) (86) International application number: PCT/US2017/044805 (87) International publication number: WO 2018/026759 (08.02.2018 Gazette 2018/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 03.08.2016 US 201615227214 (71) Applicant: Noven Pharmaceuticals, INC. Miami, FL 33186 (US)	(72) Inventors: ZHANG, Jilin Miami Florida 33186 (US) LIAO, Jun Miami Florida 33186 (US) LIU, Puchun Miami Florida 33186 (US) DINH, Steven Miami Florida 33186 (US) (74) Representative: Zacco Denmark A/S  Arne Jacobsens Allé 15 2300 Copenhagen S 2300 Copenhagen S (DK)