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EP 3 509 602 A1

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(43) Date of publication: 17.07.2019 Bulletin 2019/29 (21) Application number: 16920861.8 (22) Date of filing: 04.11.2016

(51) International Patent Classification (IPC):  A61K 31/575(2006.01) A61P 25/00(2006.01) A61K 31/569(2006.01) A61P 25/28(2006.01) (86) International application number: PCT/CN2016/104681 (87) International publication number: WO 2018/082034 (11.05.2018 Gazette 2018/19)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (71) Applicant: Trineo Biotechnology Co. Ltd New Taipei City 221 (TW)

(72) Inventors: CHEN, Teng-Hai Tainan City 733 (TW) HUANG, Cheng-Po Hsinchu City 300 (TW) CHEN, Kuang-Dee Chiayi City 600 (TW) CHEN, Mon-Tarng Tainan City 712 (TW) CHAO, I-Shuan Taoyuan City 320 (TW) WANG, Chien-Yuan Tainan City 718 (TW) HUANG, Shin Huei Taipei City 110 (TW) TSAO, Cheng Chiu Taipei City 115 (TW) (74) Representative: Lang, Christian  LangPatent Anwaltskanzlei Ingolstädter Straße 5 80807 München 80807 München (DE)