(19)
(11) EP 3 510 049 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
20.12.2023 Bulletin 2023/51

(45) Mention of the grant of the patent:
08.11.2023 Bulletin 2023/45

(21) Application number: 17768082.4

(22) Date of filing: 12.09.2017
(51) International Patent Classification (IPC): 
C07K 16/44(2006.01)
(52) Cooperative Patent Classification (CPC):
C12Y 302/0102; C12N 9/2408; C07K 2319/02; C07K 2319/06; A61P 3/00; A61P 43/00
(86) International application number:
PCT/EP2017/072945
(87) International publication number:
WO 2018/046775 (15.03.2018 Gazette 2018/11)

(54)

ACID-ALPHA GLUCOSIDASE VARIANTS AND USES THEREOF

SAURE ALPHA-GLUCOSIDASE-VARIANTEN UND VERWENDUNGEN DAVON

VARIANTS D'ALPHA-GLUCOSIDASE ACIDE ET LEURS UTILISATIONS

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 12.09.2016 EP 16306149

(43) Date of publication of application:
17.07.2019 Bulletin 2019/29

(60) Divisional application:
23208091.1

(73) Proprietors:
  • INSERM - Institut National de la Santé et de la Recherche Médicale
    75013 Paris (FR)
  • Centre National de la Recherche Scientifique
    75016 Paris (FR)
  • Association Institut de Myologie
    75013 Paris (FR)

(72) Inventors:
  • MINGOZZI, Federico
    75011 Paris (FR)
  • RONZITTI, Giuseppe
    77300 Fontainebleau (FR)
  • COLELLA, Pasqualina
    80048 S. Anastasia NA (IT)
  • PUZZO, Francesco
    Menlo Park 94025, California (US)

(74) Representative: Cabinet Becker et Associés 
25, rue Louis le Grand
75002 Paris
75002 Paris (FR)


(56) References cited: : 
WO-A1-2012/085622
WO-A1-2016/065319
US-A1- 2005 281 805
 WO-A1-2015/192092
WO-A2-2013/013017
US-A1- 2013 316 366
   
  • JEFF ZHIQIANG LU ET AL: "Genetic Engineering of a Bifunctional IgG Fusion Protein with Iduronate-2-Sulfatase", BIOCONJUGATE CHEMISTRY,, vol. 21, no. 1, 20 January 2010 (2010-01-20), pages 151-156, XP002692096, ISSN: 1043-1802, DOI: 10.1021/BC900382Q [retrieved on 2009-12-14]
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).