(19)
(11) EP 3 515 923 A1

(12)

(43) Date of publication:
31.07.2019 Bulletin 2019/31

(21) Application number: 17791943.8

(22) Date of filing: 22.09.2017
(51) International Patent Classification (IPC): 
C07F 9/6512(2006.01)
C07F 9/6561(2006.01)
 A61K 31/685(2006.01)
(86) International application number:
PCT/EP2017/073988
(87) International publication number:
WO 2018/055071 (29.03.2018 Gazette 2018/13)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 23.09.2016 GB 201616196
06.12.2016 GB 201620710
13.02.2017 GB 201702321
08.06.2017 GB 201709147

(71) Applicant: Katholieke Universiteit Leuven
3000 Leuven (BE)

(72) Inventors:
  • ANDREI, Graciela
    3000 Leuven (BE)
  • DE JONGHE, Steven
    3000 Leuven (BE)
  • GROAZ, Elisabetta
    3000 Leuven (BE)
  • HERDEWIJN, Piet
    3000 Leuven (BE)
  • LUO, Min
    3000 Leuven (BE)
  • SCHOLS, Dominique
    3000 Leuven (BE)
  • SNOECK, Robert
    3000 Leuven (BE)

(74) Representative: De Clercq & Partners 
Edgard Gevaertdreef 10a
9830 Sint-Martens-Latem
9830 Sint-Martens-Latem (BE)

   


(54) PRODRUGS OF FLUORINATED ACYCLIC NUCLEOSIDE PHOSPHONATES