(19)

(11)

EP 3 518 904 A1

(12)

(43) Date of publication: 07.08.2019 Bulletin 2019/32 (21) Application number: 17769011.2 (22) Date of filing: 11.09.2017

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61P 39/04(2006.01) A61K 31/4196(2006.01) A61P 3/00(2006.01) (86) International application number: PCT/EP2017/072747 (87) International publication number: WO 2018/059922 (05.04.2018 Gazette 2018/14)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 30.09.2016 EP 16191967 (71) Applicant: Synthon B.V. 6545 CM Nijmegen (NL)	(72) Inventors: FRADERA GELABERT, Sara 08830 Sant Boi de Llobregat (ES) VIVANCOS MARTINEZ, Marta 08830 Sant Boi de Llobregat (ES) ÁLVAREZ FERNÁNDEZ, Lisardo 08830 Sant Boi de Llobregat (ES) VELADA CALZADA, Jose 6545 CM Nijmegen (NL) (74) Representative: Overeem, Arjanne  Synthon B.V. IP Research P.O. Box 7071 6503 GN Nijmegen 6503 GN Nijmegen (NL)