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(11)

EP 3 528 630 A1

(12)

(43) Date of publication: 28.08.2019 Bulletin 2019/35 (21) Application number: 17862994.5 (22) Date of filing: 20.10.2017

(51) International Patent Classification (IPC):  A01N 63/00(2006.01) A61K 39/395(2006.01) C12N 5/071(2010.01) A61K 38/20(2006.01) C12N 5/02(2006.01) C12N 5/0735(2010.01) (86) International application number: PCT/US2017/057687 (87) International publication number: WO 2018/075940 (26.04.2018 Gazette 2018/17)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 21.10.2016 US 201662410877 P (71) Applicant: Georgia Tech Research Corporation Atlanta, GA 30332-4015 (US)	(72) Inventors: ROY, Krishnendu Atlanta Georgia 30332 (US) DWARSHUIS, Nate Atlanta Georgia 30332 (US) MADAN-LALA, Ranjna Atlanta Georgia 30332 (US) ROH, Kyung-Ho Atlanta Georgia 30332 (US) WILSON, Hannah Kathryn Atlanta Georgia 30332 (US) (74) Representative: HGF Limited  Saviour House 9 St. Saviourgate York YO1 8NQ York YO1 8NQ (GB)