(19)
(11) EP 3 532 486 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
12.01.2022 Bulletin 2022/02

(45) Mention of the grant of the patent:
22.09.2021 Bulletin 2021/38

(21) Application number: 17864112.2

(22) Date of filing: 26.10.2017
(51) International Patent Classification (IPC): 
C07K 14/47(2006.01)
A61K 38/17(2006.01)
A61K 45/06(2006.01)
A61P 3/00(2006.01)
A61P 3/06(2006.01)
A61P 3/10(2006.01)
C07K 16/24(2006.01)
 A61K 38/04(2006.01)
A61K 38/22(2006.01)
A61K 47/68(2017.01)
A61P 3/04(2006.01)
A61P 3/08(2006.01)
C07K 14/575(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 47/6883; A61P 3/04; A61K 47/68; A61K 47/6811; A61K 38/17; A61P 3/10; A61P 3/06; A61P 3/08; A61P 3/00; A61K 38/00; C07K 16/24; C07K 2317/24; C07K 2317/92; C07K 2317/21; C07K 2317/33; C07K 14/575; C07K 2319/30; A61K 45/06; A61K 38/22; A61K 2039/505; C07K 2317/565
(86) International application number:
PCT/US2017/058455
(87) International publication number:
WO 2018/081370 (03.05.2018 Gazette 2018/18)

(54)

ANTIBODY-COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE COMPOUNDS AS MODULATORS OF NEUROPEPTIDE Y RECEPTORS

ANTIKÖRPERGEKOPPELTE CYCLISCHE PEPTIDTYROSIN-TYROSIN-VERBINDUNGEN ALS MODULATOREN VON NEUROPEPTID-Y-REZEPTOREN

COMPOSÉS DE TYROSINE TYROSINE DE PEPTIDE CYCLIQUE COUPLÉS À UN ANTICORPS EN TANT QUE MODULATEURS DES RÉCEPTEURS DU NEUROPEPTIDE Y

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 27.10.2016 US 201662413586 P
27.10.2016 US 201662413613 P

(43) Date of publication of application:
04.09.2019 Bulletin 2019/36

(60) Divisional application:
21198106.3

(73) Proprietor: Janssen Pharmaceutica NV
2340 Beerse (BE)

(72) Inventors:
  • MACIELAG, Mark
    Spring House, PA 19477 (US)
  • PATCH, Raymond, J.
    Spring House, PA 19477 (US)
  • ZHANG, Rui
    Spring House, PA 19477 (US)
  • CASE, Martin, A.
    San Diego, CA 92121 (US)
  • RANGWALA, Shamina, M.
    Spring House, PA 19477 (US)
  • LEONARD, James, N.
    Spring House, PA 19477 (US)
  • CAMACHO, Raul, C.
    Spring House, PA 19477 (US)
  • HUNTER, Michael, J.
    San Diego, CA 92121 (US)
  • D'AQUINO, Katharine, E.
    Spring House, PA 19477 (US)
  • EDWARDS, Wilson
    San Diego, CA 92121 (US)
  • SWANSON, Ronald, V.
    San Diego, CA 92121 (US)
  • JIAN, Wenying
    Spring House, PA 19477 (US)
  • ZHANG, Yue-Mei
    Spring House, PA 19477 (US)
  • WALL, Mark
    Spring House, PA 19477 (US)
  • CHI, Ellen
    San Diego, CA 92121 (US)

(74) Representative: Carpmaels & Ransford LLP 
One Southampton Row
London WC1B 5HA
London WC1B 5HA (GB)


(56) References cited: : 
WO-A1-2015/197735
US-A1- 2016 108 098
 US-A1- 2015 258 209
   
  • GERMAIN ET AL.: 'Analogs of pancreatic polypeptide and peptide YY with a locked PP-fold structure are biologically active' PEPTIDES vol. 39, 2013, pages 6 - 10, XP028973917
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).