(19)
(11) EP 3 535 244 A1

(12)

(43) Date of publication:
11.09.2019 Bulletin 2019/37

(21) Application number: 17800433.9

(22) Date of filing: 02.11.2017
(51) International Patent Classification (IPC): 
C07D 221/20(2006.01)
C07D 491/107(2006.01)
A61K 31/438(2006.01)
 C07D 205/12(2006.01)
A61K 31/397(2006.01)
A61P 25/00(2006.01)
(86) International application number:
PCT/EP2017/078043
(87) International publication number:
WO 2018/083171 (11.05.2018 Gazette 2018/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 02.11.2016 WO PCT/CN2016/104349
15.12.2016 US 201662434820 P

(71) Applicant: Abbvie Deutschland GmbH & Co. KG
65189 Wiesbaden (DE)

(72) Inventors:
  • AMBERG, Wilhelm
    67061 Ludwigshafen (DE)
  • VAN BERGEIJK, Jeroen
    67061 Ludwigshafen (DE)
  • GENESTE, Herve
    67061 Ludwigshafen (DE)
  • HORNBERGER, Wilfried
    67061 Ludwigshafen (DE)
  • VAN DER KAM, Elizabeth Louise
    67061 Ludwigshafen (DE)
  • LANGE, Udo
    67061 Ludwigshafen (DE)
  • MEZLER, Mario
    67061 Ludwigshafen (DE)
  • OCHSE, Michael
    67061 Ludwigshafen (DE)
  • OELLIEN, Frank
    67061 Ludwigshafen (DE)
  • WALLESER, Patrick
    6010 Kriens (CH)
  • TURNER, Sean C
    67061 Ludwigshafen (DE)

(74) Representative: Bensiek, Stephan 
AbbVie Deutschland GmbH & Co. KG Marken & Patente (LU72/15) Knollstraße 50
67061 Ludwigshafen
67061 Ludwigshafen (DE)

   


(54) SPIRO-COMPOUNDS AS S1P MODULATORS