(19)
(11) EP 3 535 413 A1

(12)

(43) Date of publication:
11.09.2019 Bulletin 2019/37

(21) Application number: 17808237.6

(22) Date of filing: 02.11.2017
(51) International Patent Classification (IPC): 
C12Q 1/68(2018.01)
C12Q 1/6809(2018.01)
 C12Q 1/6883(2018.01)
(86) International application number:
PCT/US2017/059808
(87) International publication number:
WO 2018/085603 (11.05.2018 Gazette 2018/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 02.11.2016 US 201662416689 P
29.04.2017 WO PCT/US2017/030293

(71) Applicant: The Medical College of Wisconsin, Inc.
Milwaukee, WI 53226 (US)

(72) Inventors:
  • MITCHELL, Aoy, Tomita
    Elm Grove, WI 53122 (US)
  • MITCHELL, Michael
    Elm Grove, WI 53122 (US)
  • STAMM, Karl
    Wauwatosa, WI 53213 (US)

(74) Representative: Gill, Siân Victoria et al
Venner Shipley LLP 200 Aldersgate
London EC1A 4HD
London EC1A 4HD (GB)

   


(54) METHODS FOR ASSESSING RISK USING TOTAL AND SPECIFIC CELL-FREE DNA