(19)
(11) EP 3 538 157 A1

(12)

(43) Date of publication:
18.09.2019 Bulletin 2019/38

(21) Application number: 17797917.6

(22) Date of filing: 06.11.2017
(51) International Patent Classification (IPC): 
A61K 47/54(2017.01)
C07K 7/56(2006.01)
 A61K 51/08(2006.01)
C07K 7/06(2006.01)
(86) International application number:
PCT/EP2017/078298
(87) International publication number:
WO 2018/087028 (17.05.2018 Gazette 2018/20)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 10.11.2016 EP 16198096

(71) Applicant: Ruprecht-Karls-Universität
69117 Heidelberg (DE)

(72) Inventors:
  • BRINGS, Sebastian
    69181 Leimen (DE)
  • FLEMING, Thomas H.
    69115 Heidelberg (DE)
  • MIER, Walter
    64625 Bensheim (DE)
  • NAWROTH, Peter P.
    69181 Leimen (DE)

(74) Representative: Grahn, Sibylla Maria 
Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22
80336 München
80336 München (DE)

   


(54) METHYLGLYOXAL-SCAVENGING CYCLIC PEPTIDES AND THEIR USE FOR THE PREVENTION AND TREATMENT OF DISEASES ASSOCIATED WITH ELEVATED METHYLGLYOXAL LEVELS