(19)
(11) EP 3 543 241 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
12.10.2022 Bulletin 2022/41

(45) Mention of the grant of the patent:
07.09.2022 Bulletin 2022/36

(21) Application number: 17873122.0

(22) Date of filing: 22.11.2017
(51) International Patent Classification (IPC): 
C07D 487/04(2006.01)
A61P 19/02(2006.01)
 A61K 31/519(2006.01)
A61P 29/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/519; A61P 19/02; A61P 29/00; C07D 487/04; Y02P 20/55
(86) International application number:
PCT/CN2017/112237
(87) International publication number:
WO 2018/095320 (31.05.2018 Gazette 2018/22)

(54)

PREPARATION METHOD FOR AND INTERMEDIATE OF PYRROLO SIX-MEMBERED HETEROAROMATIC RING DERIVATIVE

HERSTELLUNGSVERFAHREN FÜR UND ZWISCHENPRODUKT VON SECHSGLIEDRIGEM HETEROAROMATISCHEM PYRROLO-RINGDERIVAT

PROCÉDÉ DE PRÉPARATION ET INTERMÉDIAIRE D'UN DÉRIVÉ DE NOYAU HÉTÉROAROMATIQUE À SIX CHAÎNONS DE PYRROLO

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 23.11.2016 CN 201611035019

(43) Date of publication of application:
25.09.2019 Bulletin 2019/39

(73) Proprietor: Jiangsu Hengrui Pharmaceuticals Co., Ltd.
Lianyungang, Jiangsu 222047 (CN)

(72) Inventors:
  • LIU, Bing
    Lianyungang Jiangsu 222047 (CN)
  • BIAN, Lin
    Lianyungang Jiangsu 222047 (CN)
  • GAO, Xiaohui
    Lianyungang Jiangsu 222047 (CN)

(74) Representative: Regimbeau 
20, rue de Chazelles
75847 Paris Cedex 17
75847 Paris Cedex 17 (FR)


(56) References cited: : 
EP-A1- 2 796 460
WO-A1-02/00661
WO-A1-2012/058645
WO-A1-2016/116025
CN-A- 102 510 865
CN-A- 104 470 927
 EP-A1- 3 006 445
WO-A1-2009/054941
WO-A1-2015/083028
WO-A2-01/42246
CN-A- 103 415 520
   
       
    Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).