(19)

(11)

EP 3 547 826 A1

(12)

(43) Date of publication: 09.10.2019 Bulletin 2019/41 (21) Application number: 17877368.5 (22) Date of filing: 01.12.2017

(51) International Patent Classification (IPC):  A01H 5/00(2018.01) C12N 5/10(2006.01) C12N 15/09(2006.01) C12N 1/13(2006.01) C12N 9/90(2006.01) C12N 15/82(2006.01) (86) International application number: PCT/US2017/064286 (87) International publication number: WO 2018/102728 (07.06.2018 Gazette 2018/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 01.12.2016 US 201662428775 P (71) Applicant: Arkansas State University-Jonesboro Jonesboro, Arkansas 72467 (US)	(72) Inventors: LORENCE, Argelia Jonesboro, AR 72404 (US) YACTAYO-CHANG, Jessica, Patricia Jonesboro, AR 72401 (US) (74) Representative: Murgitroyd & Company  Scotland House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)