(19)

(11)

EP 3 548 036 A1

(12)

(43) Date of publication: 09.10.2019 Bulletin 2019/41 (21) Application number: 17893482.4 (22) Date of filing: 02.02.2018

(51) International Patent Classification (IPC):  A61K 31/565(2006.01) A61K 47/44(2017.01) A61K 31/57(2006.01) (86) International application number: PCT/US2017/064788 (87) International publication number: WO 2018/136161 (26.07.2018 Gazette 2018/30)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 05.12.2016 US 201662430339 P 03.04.2017 US 201762481060 P (71) Applicant: Therapeuticsmd, Inc. Boca Raton, Florida 33487 (US)	(72) Inventors: AMADIO, Julia M. Boca Raton, Florida 33486 (US) BERNICK, Brian A. Boca Raton, Florida 33496 (US) MIRKIN, Sebastian Florida 33432 (US) (74) Representative: Murgitroyd & Company  Scotland House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)