(19)

(11)

EP 3 551 685 A1

(12)

(43) Date of publication: 16.10.2019 Bulletin 2019/42 (21) Application number: 17878088.8 (22) Date of filing: 05.12.2017

(51) International Patent Classification (IPC):  C08H 1/00(2006.01) A61K 39/395(2006.01) C07K 14/47(2006.01) A61P 35/00(2006.01) (86) International application number: PCT/US2017/064630 (87) International publication number: WO 2018/106644 (14.06.2018 Gazette 2018/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 07.12.2016 US 201662431357 P (71) Applicant: Innate Biotherapeutics, LLC Newton, Massachusetts 02459 (US)

(72) Inventors: REZNIK, Gabriel Oscar Bedford, Massachusetts 01730 (US) KANE, John James Cambridge, Massachusetts 02139 (US) SIEDLECKI, James Michael Burlington, Massachusetts 01803 (US) DOSTALOVA, Zuzana Cambridge, Massachusetts 02141 (US) SANSAL-CASTELLANO, Isabelle Jamaica Plain, Massachusetts 02130 (US) RUBIN-BEJERANO, Ifat Newton, Massachusetts 02459 (US) MIAO, Hua Newton, Massachusetts 02461 (US) FURFINE, Eric Steven Lincoln, Massachusetts 01773 (US) (74) Representative: Snodin, Michael D.  Park Grove IP BioCity Nottingham Pennyfoot Street Nottingham NG1 1GF Nottingham NG1 1GF (GB)