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(11)

EP 3 554 531 A1

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(43) Date of publication: 23.10.2019 Bulletin 2019/43 (21) Application number: 17703587.0 (22) Date of filing: 24.01.2017

(51) International Patent Classification (IPC):  A61K 38/17(2006.01) A61P 27/02(2006.01) (86) International application number: PCT/US2017/014754 (87) International publication number: WO 2018/139991 (02.08.2018 Gazette 2018/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (71) Applicant: MacRegen, Inc. San José, CA 95136 (US)	(72) Inventors: RUDOLF, Martin San Jose CA 95136 (US) ROIZMAN, Keith San Jose CA 95136 (US) (74) Representative: Lahrtz, Fritz  Patentanwälte Isenbruck Bösl Hörschler PartG mbB Prinzregentenstraße 68 81675 München Prinzregentenstraße 68 81675 München (DE)