(19)

(11)

EP 3 555 282 A1

(12)

(43) Date of publication: 23.10.2019 Bulletin 2019/43 (21) Application number: 17881456.2 (22) Date of filing: 14.12.2017

(51) International Patent Classification (IPC):  C12N 9/90(2006.01) C12P 19/24(2006.01) C12P 19/02(2006.01) (86) International application number: PCT/US2017/066298 (87) International publication number: WO 2018/112139 (21.06.2018 Gazette 2018/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD TN (30) Priority: 14.12.2016 US 201662434033 P (71) Applicant: Bonumose LLC Charlottesville, VA 22911 (US)	(72) Inventors: WICHELECKI, Daniel, Joseph Charlottesville, VA 22911 (US) ROGERS, Edwin, O. Charlottesville, VA 22903 (US) (74) Representative: Jacobi, Markus Alexander  Patentanwälte Isenbruck Bösl Hörschler PartG mbB Eastsite One Seckenheimer Landstrasse 4 68163 Mannheim 68163 Mannheim (DE)